Contributors Preface SECTION I THE IMMUNE SYSTEM IN HEALTH AND DISEASE 1 Introduction to the Immune System 2 The Major Histocompatibility Complex 3 Autoimmunity and Autoimmune Diseases SECTION II DISORDERS OF IMMUNE-MEDIATED INJURY 4 Systemic Lupus Erythematosus 5 Antiphospholipid Syndrome 6 Rheumatoid Arthritis 7 Acute Rheumatic Fever 8 Systemic Sclerosis (Scleroderma) and Related Disorders 9 Sjögren’s Syndrome 10 The Spondyloarthritides 11 The Vasculitis Syndromes 12 Behçet’s Syndrome 13 Relapsing Polychondritis 14 Sarcoidosis 15 IgG4-Related Disease 16 Familial Mediterranean Fever and Other Hereditary Autoinflammatory Disease 17 Polymyositis, Dermatomyositis, and Inclusion Body Myositis 18 Approach to Articular and Musculoskeletal Disorders 19 Osteoarthritis 20 Gout and Other Crystal-Associated Arthropathies 21 Infectious Arthritis 22 Fibromyalgia 23 Arthritis Associated with Systemic Disease,and Other Arthritides 24 Periarticular Disorders of the Extremities Appendix Review and Self-Assessment Index